منابع مشابه
Genetics and ischaemic stroke.
Ischaemic stroke can be caused by a number of monogenic disorders, and in such cases stroke is frequently part of a multisystem disorder. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL), due to mutations in the NOTCH: 3 gene, is increasingly appreciated as a cause of familial subcortical stroke. The genetics and phenotypes of monogenic stroke...
متن کاملPneumoviruses: Molecular Genetics and Reverse Genetics
Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...
متن کاملThe Genetics of Ischemic Stroke
Pankaj Sharma is Professor of Neurology at Royal Holloway University of London and Director of its Institute of Cardiovascular Research (ICR2UL) which is closely partnered with local hospitals Ashford & St Peters NHS Foundation Trust. PS is also consultant neurologist at Imperial College London, Editor-in-Chief of the Journal of the Royal Society of Medicine Cardiovascular Disease and Hon. Medi...
متن کاملIschemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study
BACKGROUND Although cigarette smoking is a well-established risk factor for vascular disease, the genetic mechanisms that link cigarette smoking to an increased incidence of stroke are not well understood. Genetic variations within the genes of the inflammatory pathways are thought to partially mediate this risk. Here we evaluate the association of several inflammatory gene single nucleotide po...
متن کاملAssociation of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population
BACKGROUND AND PURPOSE Ischemic stroke (IS) is the main cause of mortality and disability among the old people in China and is a multifactorial disease influenced by many factors including genetic factors like the allele for CYP 2J2. It has been demonstrated that CYP2J2 polymorphisms alter the transcriptional activity. However, studies on the association between CYP2J2-50G/T polymorphism and IS...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 2012
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100015262